Wednesday, June 27, 2007

08:00-19:15

Pre- Congress Day: From Sample Preparation to Data Analysis
Co-chairs: Juan Pablo Albar, Centro Nacional de Biotecnologia (CNB-CSIC), ProteoRed , Madrid, Spain and Patricia Palagi, Swiss Institute of Bioinformatics (SIB), Geneve, Switzerland

8:00-8:10

Welcome Address, Juan Pablo Albar, Centro Nacional de Biotecnologia (CNB-CSIC), ProteoRed , Madrid, Spain

8:10-8:40  

Section A: Sample preparation

Sample Preparation in Proteomics- An introduction.

Juan Pablo Albar, Centro Nacional de Biotecnologia (CNB-CSIC), ProteoRed , Madrid, Spain

Liquid handling: Basic concepts.
Alejandro Alvarez, Lobov Cientifica, Buenos Aires, Argentina.

9:40-9:55

Break

9:55-10:40

New advanced solutions for front end proteomic sample preparation and proteomics research

Rudolf Grimm, Agilent, California, USA

10:40-11:25 

Sample preparation for Gel-based Quantitative Differential Proteomics: 2D-DIGE
Francesc Canals, Institut de Recerca del Hospital Vall d´Hebrón (FIR-HUVH), ProteoRed , Barcelona, Spain

12:55-13:55

Lunch

13:55-14:40

Ion mobility spectrometry coupled with time-of-flight mass spectrometry for detailed protein and peptide structure studies
Jim Langridge, Waters Corporation, Atlas Park, Simonsway, Manchester, UK

14:40-15:25

Section C: Mass Spectrometry and Bioinformatics
MALDI-MS, high energy MS/MS and MSn technologies and their application in protein identification and characterization
Emmanuel Raptakis, Shimadzu Biotech, Manchester, UK

15:25-16:10

MALDI tissue imaging: mass spectrometric localization of biomarkers in tissue slices
Michael Easterling, Bruker Daltonics, USA

16:10-16:25

Break

17:40-19:00

MS bioinformatics analysis for proteomics: MS identification
Patricia Palagi, Swiss Institute of Bioinformatics (SIB), Geneve, Switzerland

19:00-19:15

Questions and Answers
Moderator: Silvia Moreno, Facultad de Ciencias Exactas, UBA, Argentina.
Close: Juan Pablo Albar, Centro Nacional de Biotecnologia (CNB-CSIC), ProteoRed , Madrid, Spain

13:30-18:30

CVI HUPO Initiatives; Plan, Progress and Perspectives.
CoChairs: Peipei Ping UCLA, School of Medicine, Los Angeles, California,  USA (HUPO Secretary).- Mario H. Genero - Universidad Austral, Facultad de Ciencias Biomédicas, Pilar, Buenos Aires, Argentina. HUPO Council Member - LAHUPO President

A novel role for Bmx tyrosine kinase in cardiac physiology: insights from proteomics-  Thomas Vondriska UCLA, School of Medicine, Los Angeles, California

Considerations for Proteomics Activities for the Development of Novel in vitro Diagnostics;  Frank Vitzhum; Dade Behring Marburg GmbH, Marburg, Germany.

Tandem TOF Mass Spectrometer Developed at the Johns Hopkins Center for the Proteomics of Ischemia and Hypoxia and its Application to the Albuminome. Bob Cotter Professor of Pharmacology and Molecular Sciences Professor of Biophysics and Biophysical Chemistry - Director: Middle Atlantic Mass Spectrometry LaborAatory Johns Hopkins University School of Medicine- MD- USA

The Congress will officially start with the Congress Welcome Reception on Wednesday June 27, 2007 . The Congress Scientific Program will take place on Thursday June 28 and will finish on Saturday June 30, 2007 in the evening.

Thursday, June 28, 2007

08:00-09:00

Morning Session: HUPO Initiatives Day
Co-Chairs: Catherine Fenselau, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, USA -HUPO Senior Vice-President and Peipei Ping, UCLA, School of Medicine, Los Angeles, California,  USA -HUPO Secretary

8:00-8:05

Welcome Address   
Co-chairs: Fernando Vivanco, Fundacion Jiménez Díaz, Madrid, España, and Mario Hugo Genero, Universidad Austral, Facultad de Ciencias Biomédicas, Pilar, Buenos Aires, Argentina - LAHUPO President.

8:05-8:10  

Welcome Address
John J.M. Bergeron, Mc Gill University , Montreal , Canada - HUPO Past President.

8:10-9:00

Opening Address: HUPO Initiatives - An Update
John J.M. Bergeron, Mc Gill University , Montreal , Canada - HUPO Past President.

09:00-10:00 

Break, Posters and Exhibits; Exhibit Hall

10:00-12:30  

HUPO Initiatives (Cont.); Plan, Progress, and Perspectives
Co-Chairs: Catherine Fenselau, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, USA - HUPO Senior Vice-President and Mark S. Baker, Australian Proteome Analysis Facility (APAF) LTD, Sydney, NSW, Australia.

10:00-10:45

Human Liver Proteome Project (HLPP)
Laura Beretta, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

10:45-11:30

Human Brain Proteome Project (HBPP)
Michael Hamacher, Ruhr-University of Bochum, Germany.

11:30-12:15 

New Cardiovascular Initiative (CVI-HUPO)
Peipei Ping, UCLA, School of Medicine, Los Angeles, California, USA - HUPO Secretary-

12:15-12:30 

Questions and Answers
Moderator: Rolando Rivera Pomar, Centro Regional de Estudios Genómicos, UNLP y LAHUPO, Argentina.

12:30-14:30 

Lunch and Industrial Sponsored Symposia (LC/MS Workflow for Biomarker Identification and Validation, Dustin Yaworsky , Agilent, California, USA)

14:30-18:15  

Afternoon Session: HUPO Initiatives: Plan, Progress and Perspectives.
Co-Chairs: Peipei Ping, UCLA, School of Medicine , Los Angeles , California ,  USA -HUPO Secretary and Mario H. Genero, Universidad Austral - Buenos Aires, Argentina  - LAHUPO President

14:30-15:00
 

Proteomics and Informatics Strategies for Label-Free Biomarker Discovery in Human Plasma
Amy M. Zumwalt, Strategic Marketing Specialist - Proteomics, Thermo Fisher Scientific, San Jose, California, USA

15:00-15:30

CVI-HUPO Networking
Mario H Genero, Universidad Austral - Buenos Aires, Argentina  - LAHUPO President

15:30-16:30

Break, Posters and Exhibits; Exhibit Hall

16:30-17:00

Human Disease Glycomics Proteome Initiative
Naoyuki Taniguchi, Osaka University , Japan -Chair HDGPI-HUPO

17:30-18:00

Search of molecular targets for novel anti-parasitic drugs: integration of genomic, functional proteomic and structural dta of trypanosome macromolecular complexes.
Mariano Levin, INGEBI - Laboratorio de Biología Molecular de Enfermedad de Chagas, Argentina.

18:00-18:15

Questions and Answers
Moderator: Alicia Couto, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina

Friday, June 29

8:00-13:00 

Morning Session: Proteomics in Biomedical Discoveries
Co-Chairs:  Rolf Apweiler, EMBL-EBI, Cambridge, UK  -HUPO President- and Fernando Vivanco,  Fundacion Jiménez Díaz, Madrid, España.

8:00-8:30

Immunoprecipitation with slice-and-dice proteomics to identify cancer "metastasome" protein interactions.
Mark Baker, Australian Proteome Analysis Facility Ltd (APAF), Macquarie University, Sydney, Australia - HUPO & AO-HUPO Council member.

8:30-9:00

Analysis of human plasma proteome in Acute Coronary Syndromes: identification of potential novel biomarkers. Fernando Vivanco, Fundacion Jiménez Díaz, Madrid, España.

9:00-10:00

Break, Posters and Exhibits.  Exhibit Hall

10:00-10:30

Proteomics of liver disease
José María Mato, CIC-Biogune, Parque Tecnologico de Bizkaia, Bizkaia, España.

10:30-11:00

State of the Art Lecture:  Integrative Analysis of the Liver Proteome as a Strategy for Liver Disease Biomarker Discovery
Laura Beretta, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

11:30-12:00

Bacterial vaccines: Identification of new immunogens by omics strategies
Daniela F. Hozbor , Instituto de Bioquímica y Biología Molecular, Universidad Nacional de La Plata, La Plata, Argentina

12:00-12:30

Autophosphorylation pattern and substrate recruitment mechanism in S/T protein kinases from Mycobacterium tuberculosis
Rosario Durán , Unidad de Bioquimica Analitica y Proteomica, IIBCE y Instituto Pasteur de Montevideo, Uruguay.

12:30-12:45

Questions and Answers
Moderator: Marcelo Silva, Hepatology Department, Austral Hospital, Pilar, Buenos Aires, Argentina.

12:45-14:30

Lunch and Industrial Sponsored Symposia. (Biomarkers and quantitation in Proteomics, Alberto Sánchez , Bruker Daltonics, España)

14:30-18:15  

Afternoon Session: Human Disease Proteomics
Co-Chairs: Jan van Oostrum, Novartis Institute of Biomedical Research, Basel, Switzerland and Andrea Llera, Fundación Instituto Leloir, Buenos Aires, Argentina, LAHUPO Secretary.

14:30-15:00

State of the Art Lecture:  Linking proteomics to signaling pathways and diseases
Jan van Oostrum, Novartis Institute of Biomedical Research, Basel, Switzerland.

15:00-15:30

Proteomic analysis of ribonucleoprotein complexes during apoptosis .
Rolando Rivera Pomar , Centro Regional de Estudios Genómicos, UNLP and LAHUPO, Argentina.

15:30-16:00

Exploring the Cardiac Mitochondrial Proteome: Significance in myocardial function and diseases.
Peipei Ping, UCLA, School of Medicine, Los Angeles, California, USA -HUPO Secretary.

16:00-16:50

Break, Posters and Exhibits - Exhibit Hall

A proteomic approach to study the molecular mechanism of the protumoral protein SPARC.
Andrea Llera , Fundación Instituto Leloir, Buenos Aires, Argentina. LAHUPO Secretary.

17:10-17:30

Absolute label-free LC-MS quantification of diagnostic Gaucher Disease Markers
Jim Langridge, Waters Corporation, Atlas Park , Simonsway, Manchester , UK .

17:30-18:00

Tandem Time-of-Flight Mass Spectrometry and Biomarkers from the CSF
Robert Cotter, Johns Hopkins Medical School , Baltimore , MD , USA .

18:00-18:15

Questions and Answers
Moderator: Norberto A. Guzman Departments of Bioanalysis and Drug Metabolism, Johnson & Johnson Pharmaceutical Research and Development, Raritan, NJ, U.S.A.

20:30 -24:00

Dinner and Tango Show
Ticket required. 

Saturday, June 30

8:00-13:00

8:00-8:30

Disease Proteomics: Proteomic analysis of nasal fluid derived from children suffering Influenza virus infection.
Luis M. Terán. INER-Biomedicine Foundation, Mexico.

8:30-9:00

9:00-9:30

The use of solid-phase extraction method coupled on-line to capillary electrophoresis for the analysis of peptides.
Nora M. Vizioli, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires, Buenos Aires, Argentina.

9:30-10:00

Analytical Nanotechnology in Proteomics.
Alexander Archakov, Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, Russia.

10:00-11:00

Break, Posters and Exhibits.  Exhibit Hall

11:00-11:30

Integration of a residue specific chemical cleavage into proteomic strategies.
Catherine Fenselau,  Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, USA

11:30-12:00

12:00-12:30

Latest advancements in HPLC-Chip/MS with applications to proteomics and glycomics research
Rudolf Grimm, Proteomics and Metabolomics Market Development Manager, Agilent Technologies, Santa Clara , CA , USA .

12:30-12:45

Questions and Answers
Moderator: Luis M. Teran, INER-Biomedicine Foundation, Mexico

12:45-14:30

Lunch

14:30-18:45 

Afternoon Session: Disease Biomarkers
Co-chairs: Helmut E.  Meyer, Medizinisches Proteom-Center, Ruhr-Universitaet, Bochum, Germany and Pablo Argibay, Instituto de Investigaciones Biotecnológicas, Hospital Italiano, Buenos Aires, Argentina.

14:30-15:00

High-Performance Proteomics as a Tool in Biomarker Discovery.
Helmut E.  Meyer, Medizinisches Proteom-Center, Ruhr-Universitaet, Bochum, Germany.

15:00-15:30

The protein microscope to visualise organellar subproteomes by tandem mass spectrometry
John J.M Bergeron, Mc Gill University, Montreal, Canada, HUPO Past President

15:30-16:00

Immunodepletion - can it show us what´s beneath the tip of the plasma proteomic iceberg?.
Mark S. Barker, Australian Proteome Analysis Facility Ltd (APAF), Macquarie University, Sydney, Australia - HUPO & AO-HUPO Council member

16:00-16:45

Break, Posters and Exhibits - Exhibit Hall

17:15-17:45

Large-scale biology and data representation: where do we stand? A former bench scientist´s point of view.
Pierre Legrain, Chef du Department de Biologie Joliot - Curie, France .

17:45-18:15  

Keynote Lecture: The challenge to move proteomics: beyond parts list construction.
Rolf Apweiler, EMBL-EBI, Hinxton, UK  

18:15-18:30

Questions and Answers
Moderator: Peipei Ping, UCLA, School of Medicine, Los Angeles, California,  USA -HUPO Secretary

18:30-18:45

Closing Remarks
Fernando Vivanco, Fundacion Jiménez Díaz, Madrid, Spain, and Mario Hugo Genero, Universidad Austral, Facultad de Ciencias Biomédicas, Pilar, Buenos Aires, Argentina. LAHUPO President.

18:45-19:00